BDBM136735 US11547697, Compound 327::US9682141, 327

SMILES CC(=O)N1CCN(CC1)C1CN(C1)c1cnc2ccc(cc2n1)-c1ccc2oc(N)nc2c1

InChI Key InChIKey=WKDNQONLGXOZRG-HRNNMHKYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 136735   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Intellikine

US Patent
LigandPNGBDBM136735(US11547697, Compound 327 | US9682141, 327)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The kinase reaction is performed in a white 384 well microtitre plate. The total reaction volume is 20 ul per well and the reaction buffer compositio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Intellikine

US Patent
LigandPNGBDBM136735(US11547697, Compound 327 | US9682141, 327)
Affinity DataIC50: >1.00E+4nMAssay Description:The compounds described herein can be tested against recombinant mTOR (Invitrogen) in an assay containing 50 mM HEPES, pH 7.5, 1 mM EGTA, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent